The Mechanisms of Radiation-Induced Bystander Effect

Authors

  • Gh Hadadi department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran
  • M Fardid Health Management and Economics Research Center, Iran University of Medical Science, Tehran, Iran.
  • M Najafi department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran
  • R Fardid department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran
Abstract:

The radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. Responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. These changes are confirmed by results of some In-Vivo studies. Most well-known important factors affecting radiation-induced bystander effect include free radicals, immune system factors, expression changes of some genes involved in inflammation pathway and epigenetic factors.

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Journal title

volume 4  issue 4

pages  -

publication date 2014-12-01

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